{"product_id":"recombinant-mouse-alpha-1-antitrypsin-1-1-serpin-a1e-c-6his-pksm041392","title":"Recombinant Mouse Alpha-1-antitrypsin 1-1\/Serpin A1e (C-6His) - PKSM041392","description":"\u003cp\u003eRecombinant Mouse Alpha-1-antitrypsin 1-1\/Serpin A1e (C-6His)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSM041392-10, PKSM041392-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Serpin A1e\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Alpha-1-antitrypsin 1-5; Alpha-1 protease inhibitor 5; Serine protease inhibitor 1-5; Serine protease inhibitor A1e; Serpin A1e; Serpina1e; Dom5; Spi1-5\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q00898\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Mouse\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q00898\u003c\/p\u003e\n\n\u003cp\u003eBackground: Alpha-1-antitrypsin 1-5(SERPIN A1) is a secreted protein and belongs to the serpin family. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. Mouse SERPIN A1 is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema orliver disease. Several transcript variants encoding the same protein have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Glu25-Lys413\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 44.5 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 47-60 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43072219676851,"sku":"PKSM041392-10","price":310.8,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43072219709619,"sku":"PKSM041392-50","price":912.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_7ae36a0b-7400-455a-9f51-0d9c9ed4cce4.png?v=1708684395","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-alpha-1-antitrypsin-1-1-serpin-a1e-c-6his-pksm041392","provider":"AFSBio Inc.","version":"1.0","type":"link"}