{"product_id":"recombinant-mouse-angiopoietin-2-ang-2-angpt2275-496-protein-rp01744","title":"Recombinant Mouse Angiopoietin-2\/ANG-2\/ANGPT2(275-496) Protein - RP01744","description":"\u003cp\u003eRecombinant Mouse Angiopoietin-2\/ANG-2\/ANGPT2(275-496) Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01744-10, RP01744-20, RP01744-50, RP01744-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Mouse Angiopoietin-2\/ANG-2\/ANGPT2(275-496) Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Lys275-Phe496) of mouse Angiopoietin-2\/ANG-2\/ANGPT2 (Accession #NP_031452.2) fused with a 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Ang2; Agpt2; Ang-2\u003c\/p\u003e\n\n\u003cp\u003eSWISS: O35608\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 11601\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine kinase receptor, Tie-2, found primarily on the luminal surface of endothelial cells. ANG-2's role in angiogenesis generally is considered as an antagonist for ANG1, inhibiting ANG1-promoted Tie2 signaling, which is critical for blood vessel maturation and stabilization\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: KEEQTTFRDCAEIFKSGLTTSGIYTLTFPNSTEEIKAYCDMDVGGGGWTVIQHREDGSVDFQRTWKEYKEGFGSPLGEYWLGNEFVSQLTGQHRYVLKIQLKDWEGNEAHSLYDHFYLAGEESNYRIHLTGLTGTAGKISSISQPGSDFSTKDSDNDKCICKCSQMLSGGWWFDACGPSNLNGQYYPQKQNTNKFNGIKWYYWKGSGYSLKATTMMIRPADF\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198251131059,"sku":"RP01744-10","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198251163827,"sku":"RP01744-20","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198251196595,"sku":"RP01744-50","price":350.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198251229363,"sku":"RP01744-100","price":560.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_4dfd6616-03d0-4456-b0be-328ed94cb93b.png?v=1766959740","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-angiopoietin-2-ang-2-angpt2275-496-protein-rp01744","provider":"AFSBio Inc.","version":"1.0","type":"link"}