{"product_id":"recombinant-mouse-apcs-sap-protein-his-tagactive-pksm040858","title":"Recombinant Mouse APCS\/SAP Protein (His Tag)(Active) - PKSM040858","description":"Recombinant Mouse APCS\/SAP Protein (His Tag)(Active)\n\nSize: 100μg\n\nCatalogue Number: PKSM040858-100\n\nCitations, Manuals and MSDS Available upon request.\n\nAbbreviation: APCS; SAP\n\nTarget Symptom: APCS; PTX2; SAP; 9.5S alpha-1-glycoprotein; Serum amyloid P; MGC88159; PTX2serum amyloid P-component; SAP pentaxin-related\n\nTarget Species: Mouse\n\nExpression Host: HEK293 Cells\n\nApplication: ELISA\n\nFusion Tag: C-His\n\nAccession: NP_035448.2\n\nBackground: Serum amyloid P component (SAP) is the identical serum form of amyloid P component (AP), a highly preserved plasma protein named for its ubiquitous presence in amyloid deposits. As a normal plasma protein first identified as the pentagonal constituent of in vivo pathological deposits called \" amyloid\" . Serum amyloid P component represents another member of the pentraxin family, a highly conserved group of molecules that may play a role in innate immunity. SAP is a key negative regulator for innate immune responses to DNA and may be partly responsible for the insufficient immune responses after DNA vaccinations in humans. SAP suppression may be a novel strategy for improving efficacy of human DNA vaccines and requires further clinical investigations.\n\nActivity: 1. Immobilized mouse APCS at 10 μg\/ml (100 μl\/well) can bind biotinylated human Fibronectin Fragment 2 with a linear ranger of 0.625-5 μg\/ml. \n2. Measured by its ability to bind mouse CD64-AVI in a functional ELISA. \n\nSequence: Met 1-Glu 224\n\nPurity: \u0026gt; 90 % as determined by reducing SDS-PAGE.\n\nFormulation: Lyophilized from sterile PBS, pH 7.4\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\nPlease refer to the specific buffer information in the printed manual.\n\nReconstitution: Please refer to the printed manual for detailed information.\n\nEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\n\nCalculated MW: 25.3 kDa\n\nObserved MW: 28 kDa\n\nStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\n\nShipping: This product is provided as lyophilized powder which is shipped with ice packs.\n\nResearch Use Only","brand":"Elabscience","offers":[{"title":"Default Title","offer_id":43104273694899,"sku":"PKSM040858-100","price":1024.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_b3048b4a-86cb-434c-8355-2b4b497b4924.png?v=1709293555","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-apcs-sap-protein-his-tagactive-pksm040858","provider":"AFSBio Inc.","version":"1.0","type":"link"}