{"product_id":"recombinant-mouse-april-tnfsf13-protein-fc-tag-pksm041367","title":"Recombinant Mouse APRIL\/TNFSF13 Protein (Fc Tag) - PKSM041367","description":"\u003cp\u003eRecombinant Mouse APRIL\/TNFSF13 Protein (Fc Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSM041367-10, PKSM041367-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: APRIL; TNFSF13\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: A proliferation-inducing ligand; TNFSF13; TALL-2; TRDL-1; CD256\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9D777\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Mouse\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-Fc\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q9D777\u003c\/p\u003e\n\n\u003cp\u003eBackground: Tumor necrosis factor ligand superfamily member 13 belongs to the tumor necrosis factor family. It is also known as APRIL, TALL2, TRDL1, and CD256. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to release the active 17 kDa soluble molecule. TNFSF13 is a Cytokine that binds to TNFRSF13B\/TACI and to TNFRSF17\/BCMA and plays a role in the regulation of tumor cell growth. It expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages. Its expression by CD4+ T cells inhibits the production of Th2 cytokines and allergic inflammation.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Ala96-Leu240\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 42.7 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 50-60 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43072217514163,"sku":"PKSM041367-10","price":155.4,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43072217546931,"sku":"PKSM041367-50","price":415.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_2813f5f4-377c-45b3-a10a-487ff682826a.png?v=1708684362","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-april-tnfsf13-protein-fc-tag-pksm041367","provider":"AFSBio Inc.","version":"1.0","type":"link"}