{"product_id":"recombinant-mouse-ccl2-mcp-1-protein-rp01626","title":"Recombinant Mouse CCL2\/MCP-1 Protein - RP01626","description":"\u003cp\u003eRecombinant Mouse CCL2\/MCP-1 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01626-10, RP01626-20, RP01626-50, RP01626-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Mouse CCL2\/MCP-1 Protein is produced by Pichia expression system. The target protein is expressed with sequence (Gln 24-Asn148) of mouse CCL2\/MCP-1 (Accession #NP_035463.1) fused with no additional amino acid.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: C-C motif chemokine ligand 2, CCL2, GDCF-2, HC11, HSMCR30, MCAF, Mcp1, MCP-1, SCYA2, SMC-CF, CCL2\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P10148\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 20296\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Monocyte chemoattractant protein 1 (MCP-1), also called CCL2, belongs to a group of CC chemokines located in chromosome 17q11.2. MCP-1 protein interacts with chemokine C-C motif receptor 2 (CCR2) to activate and recruit monocytes, macrophages, CD4+ T cells and immature dendritic cells to the site of infection. The presence of MCP-1 protein in an adequate concentration is important for granuloma formation and M. tuberculosis clearance.\u003c\/p\u003e\n\n\u003cp\u003eBio-Activity: 1.Measured by the ability to inhibit the proliferation of HUVEC(Human Umbilical Vein Endothelial Cells).The ED50 for this effect is 0.20-0.80 ng\/mL.|2.Measured by its ability to chemoattract THP-1 cells. The ED50 for this effect is typically 2.87-11.48 ng\/mL.\u003c\/p\u003e\n\n\u003cp\u003eSource: Pichia\u003c\/p\u003e\n\n\u003cp\u003eTag: No tag\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: QPDAVNAPLTCCYSFTSKMIPMSRLESYKRITSSRCPKEAVVFVTKLKREVCADPKKEWVQTYIKNLDRNQMRSEPTTLFKTASALRSSAPLNVKLTRKSEANASTTFSTTTSSTSVGVTSVTVN\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198338326707,"sku":"RP01626-10","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198338359475,"sku":"RP01626-20","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198338392243,"sku":"RP01626-50","price":350.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198338425011,"sku":"RP01626-100","price":560.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_8dbe3c1e-50a7-4fe6-bfa3-ba022d177347.png?v=1766960768","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-ccl2-mcp-1-protein-rp01626","provider":"AFSBio Inc.","version":"1.0","type":"link"}