{"product_id":"recombinant-mouse-cd16-protein-his-tagactive-pksm040733","title":"Recombinant Mouse CD16 Protein (His Tag)(Active) - PKSM040733","description":"Recombinant Mouse CD16 Protein (His Tag)(Active)\n\nSize: 100μg\n\nCatalogue Number: PKSM040733-100\n\nCitations, Manuals and MSDS Available upon request.\n\nAbbreviation: CD16\n\nTarget Symptom: CD16 Protein; Mouse\n\nTarget Species: Mouse\n\nExpression Host: HEK293 Cells\n\nApplication: ELISA\n\nFusion Tag: C-His\n\nUNIProt ID: P08508\n\nAccession: P08508-1\n\nBackground: Fc receptors bind the most common class of antibody, IgG, are called Fc gamma receptors (Fcγ R). Fcγ R is divided into three classes, Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). CD16 protein is a multifunctional, low\/intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. Mouse CD16 is encoded by a single gene, while, human CD16 is expressed as two distinct forms (CD16a\/Fcγ RIIIa and CD16b\/Fcγ RIIIb) encoded by two different highly homologous genes in a cell type-specific manner. CD16 is involved in phagocytosis, secretion of enzymes, inflammatory mediators, antibody-dependent cellular cytotoxicity (ADCC), and clearance of immune complexes.\n\nActivity: Immobilized mouse FCGR3-His at 10 μg\/ml (100 μl\/well) can bind biotinylated human IgG1The EC50 of biotinylated human IgG1 is 0.12-0.28 μg\/ml.\n\nSequence: Met 1-Thr 215\n\nPurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\n\nFormulation: Lyophilized from sterile PBS, pH 7.4\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\nPlease refer to the specific buffer information in the printed manual.\n\nReconstitution: Please refer to the printed manual for detailed information.\n\nEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\n\nCalculated MW: 22.6 kDa\n\nStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\n\nShipping: This product is provided as lyophilized powder which is shipped with ice packs.\n\nResearch Use Only","brand":"Elabscience","offers":[{"title":"Default Title","offer_id":43107395010739,"sku":"PKSM040733-100","price":1024.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_97c5b7df-678a-4fad-a842-61e95c74cf0b.png?v=1709383078","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-cd16-protein-his-tagactive-pksm040733","provider":"AFSBio Inc.","version":"1.0","type":"link"}