{"product_id":"recombinant-mouse-cd36-scarb3-protein-fc-tagactive-pksm041294","title":"Recombinant Mouse CD36\/SCARB3 Protein (Fc Tag)(Active) - PKSM041294","description":"\u003cp\u003eRecombinant Mouse CD36\/SCARB3 Protein (Fc Tag)(Active)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSM041294-10, PKSM041294-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CD36; SCARB3\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Glycoprotein IIIb; GPIIIB; PAS IV; PAS-4; Platelet glycoprotein IV; GPIV; CD36\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Mouse\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eApplication: ELISA\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-Fc\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q08857\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q08857\u003c\/p\u003e\n\n\u003cp\u003eBackground: Dermatopontin is a widely expressed noncollagenous protein component of the extracellular matrix. It is a 22 kDa molecule that is tyrosine sulfated but not glycosylated. Dermatopontin is down regulated in fibrotic growths such as leiomyoma and scar tissue, inhibits cell proliferation, accelerates collagen fibril formation, and stabilizes collagen fibrils against low-temperature dissociation, Dermatopontin deficient mice exhibit altered collagen matrix deposition and organization. Dermatopontin seems to mediate adhesion by cell surface integrin binding, may serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment, and enhances TGFB1 activity (By similarity). Dermatopontin promotes bone mineralization under the control of the vitamin D receptor and inhibits BMP-2 effects on osteoblast precursors.\u003c\/p\u003e\n\n\u003cp\u003eActivity: Immobilized Mouse CD36-Fc at 10μg\/ml(100 μl\/well) can bind Human RSPO1-His(Cat: PKSH033007). The ED50 of Mouse CD36-Fc is 0.07 ug\/mL\u003c\/p\u003e\n\n\u003cp\u003eSequence: Gly30-Lys439\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 73.5 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 100-130 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43118127939763,"sku":"PKSM041294-10","price":249.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43118127972531,"sku":"PKSM041294-50","price":732.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_4f329e15-e6ae-40b4-841c-187d6f803c6f.png?v=1709636745","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-cd36-scarb3-protein-fc-tagactive-pksm041294","provider":"AFSBio Inc.","version":"1.0","type":"link"}