{"product_id":"recombinant-mouse-coagulation-factor-ix-f9-protein-his-tag-pdmm100001","title":"Recombinant Mouse Coagulation Factor IX\/F9 Protein (His Tag) - PDMM100001","description":"\u003cp\u003eRecombinant Mouse Coagulation Factor IX\/F9 Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μg, 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PDMM100001-20, PDMM100001-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Coagulation Factor IX; F9\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: AW111646; Cf-9; Cf9\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P16294\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Mouse\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-His\u003c\/p\u003e\n\n\u003cp\u003eAccession: P16294\u003c\/p\u003e\n\n\u003cp\u003eBackground: Coagulation factor IX, also known as Christmas factor, Plasma thromboplastin component and PTC, is a secreted protein which belongs to the peptidase S1 family. Coagulation factor IX \/ F9 contains two EGF-like domains, one Gla (gamma-carboxy-glutamate) domain and one peptidase S1 domain. Coagulation factor IX \/ F9 is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca2+ons, phospholipids, and factor VIIIa. Defects in Coagulation factor IX \/ F9 are the cause of thrombophilia due to factor IX defect which is a hemostatic disorder characterized by a tendency to thrombosis. Defects in Coagulation factor IX \/ F9 are also the cause of recessive X-linked hemophilia B ( HEMB ) which also known as Christmas disease.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met 1-Thr 471\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 51.3 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 60-80 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"20μg","offer_id":43149107232947,"sku":"PDMM100001-20","price":264.6,"currency_code":"CAD","in_stock":true},{"title":"100μg","offer_id":43149107265715,"sku":"PDMM100001-100","price":418.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_729a37e0-5a0c-498b-b466-60a2d31779b6.png?v=1710340740","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-coagulation-factor-ix-f9-protein-his-tag-pdmm100001","provider":"AFSBio Inc.","version":"1.0","type":"link"}