{"product_id":"recombinant-mouse-ep-cam-trop-1-cd326-protein-rp01570","title":"Recombinant Mouse Ep-CAM\/TROP-1\/CD326 Protein - RP01570","description":"\u003cp\u003eRecombinant Mouse Ep-CAM\/TROP-1\/CD326 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01570-10, RP01570-20, RP01570-50, RP01570-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Mouse Ep-CAM\/TROP-1\/CD326 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln24-Thr266) of mouse Ep-CAM\/TROP-1\/CD326 (Accession #NP_032558.2) fused with a 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: 17-1A, 323\/A3, ACSTD1, CD326, EGP-2, EGP314, EGP40, EpCAM, MOC31, TACST-1, TACSTD1, TROP1, EpCAM\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q99JW5\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 17075\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Epithelial Cellular Adhesion Molecule (Ep-CAM), also known as EGP314, mEGP314, Protein 289A, Tumor-associated calcium signal transducer 1, CD326, belongs to the EPCAM family. Its ’ monomer subunit structureinteracts with phosphorylated CLDN7. Ep-CAM may act as a physical homophilic interaction molecule betweenintestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providingimmunological barrier as a first line of defense against mucosal infection. It plays a role in embryonic stem cellsproliferation and differentiation. It also up-regulates the expression of FABP5, MYC and cyclins A and E. Thepost-translational modification glycosylation at Asn-198 is crucial for protein stability.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: QRDCVCDNYKLATSCSLNEYGECQCTSYGTQNTVICSKLASKCLAMKAEMTHSKSGRRIKPEGAIQNNDGLYDPDCDEQGLFKAKQCNGTATCWCVNTAGVRRTDKDTEITCSERVRTYWIIIELKHKERESPYDHQSLQTALQEAFTSRYKLNQKFIKNIMYENNVITIDLMQNSSQKTQDDVDIADVAYYFEKDVKGESLFHSSKSMDLRVNGEPLDLDPGQTLIYYVDEKAPEFSMQGLT\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198240809139,"sku":"RP01570-10","price":182.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198240841907,"sku":"RP01570-20","price":217.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198240874675,"sku":"RP01570-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198240907443,"sku":"RP01570-100","price":420.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_5256a330-c1f5-4dc7-8649-c9a00270ce83.png?v=1766959614","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-ep-cam-trop-1-cd326-protein-rp01570","provider":"AFSBio Inc.","version":"1.0","type":"link"}