{"product_id":"recombinant-mouse-epo-r-epor-protein-rp01732","title":"Recombinant Mouse EPO-R\/Epor Protein - RP01732","description":"\u003cp\u003eRecombinant Mouse EPO-R\/Epor Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01732-10, RP01732-20, RP01732-50, RP01732-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Mouse EPO-R\/Epor Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala25-Pro249) of mouse EPO-R\/Epor (Accession #NP_034279.3) fused with and a 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: EPO-R; Epor\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P14753\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 13857\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Erythropoietin (EPO) is the major glycoprotein hormone regulator of mammalian erythropoiesis, and is produced by kidney and liver in an oxygen-dependent manner. The biological effects of EPO are mediated by the specific erythropoietin receptor (EPOR\/EPO Receptor) on bone marrow erythroblasts, which transmits signals important for both proliferation and differentiation along the erythroid lineage. EPOR protein is a type a… single-transmembrane cytokine receptor, and belongs to the homodimerizing subclass which functions as ligand-induced or ligand-stabilized homodimers. EPOR signaling prevents neuronal death and ischemic injury. Recent studies have shown that EPO and EPOR protein may be involved in carcinogenesis, angiogenesis, and invasion.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: APSPSLPDPKFESKAALLASRGSEELLCFTQRLEDLVCFWEEAASSGMDFNYSFSYQLEGESRKSCSLHQAPTVRGSVRFWCSLPTADTSSFVPLELQVTEASGSPRYHRIIHINEVVLLDAPAGLLARRAEEGSHVVLRWLPPPGAPMTTHIRYEVDVSAGNRAGGTQRVEVLEGRTECVLSNLRGGTRYTFAVRARMAEPSFSGFWSAWSEPASLLTASDLDP\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198269644979,"sku":"RP01732-10","price":196.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198269677747,"sku":"RP01732-20","price":266.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198269710515,"sku":"RP01732-50","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198269743283,"sku":"RP01732-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_5ed02f56-7428-4dde-ad15-73d2ecf4ffdb.png?v=1766959941","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-epo-r-epor-protein-rp01732","provider":"AFSBio Inc.","version":"1.0","type":"link"}