{"product_id":"recombinant-mouse-fabp4-a-fabp-albp-protein-rp01462","title":"Recombinant Mouse FABP4\/A-FABP\/ALBP Protein - RP01462","description":"\u003cp\u003eRecombinant Mouse FABP4\/A-FABP\/ALBP Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01462-10, RP01462-20, RP01462-50, RP01462-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Mouse FABP4\/A-FABP\/ALBP Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Cys2-Ala132) of mouse FABP4\/A-FABP (Accession #NP_077717.1) fused with a 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Ap2, P15, ALBP, Lbpl, AFABP, 422\/aP2, ALBP\/Ap2, FABP4\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P04117\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 11770\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Fatty acid-binding protein, adipocyte, also known as Adipocyte-type fatty acid-binding protein, Fatty acid-binding protein 4, Adipocyte lipid-binding protein, and FABP4, is a cytoplasm protein which belongs to thecalycin superfamily and Fatty-acid binding protein (FABP) family. In familial combined hyperlipidemia (FCHL), FABP4 correlated to body mass index (BMI), waist circumference and homeostasis model assessment (HOMA) index.FABP4 levels were associated with triglyceride-rich lipoproteins. In humans serum FABP4 levels correlate significantly with features of PCOS. It appears to be a determinant of atherogenic dyslipidemia. FABP4 pathway mediates the sebaceous gland hyperplasia in keratinocyte-specific Pten-null mice. FABP4 concentration significantly increased with an increasing of MS features and was strongly correlated with body-mass index, triglycerides, HDL-cholesterol concentrations and blood pressure. Patients in the highest quartile of FABP4 presented a six-fold increased odds ratio for MS and a three-fold increased odds for LD, adjusted by age, sex, body-mass index and the antiretroviral therapy. FABP4 is a strong plasma marker of metabolic disturbances in HIV-infected patients, and therefore, could serve to guide therapeutic intervention in this group of patients.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: CDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDLVTIRSESTFKNTEISFKLGVEFDEITADDRKVKSIITLDGGALVQVQKWDGKSTTIKRKRDGDKLVVECVMKGVTSTRVYERA\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198276231347,"sku":"RP01462-10","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198276264115,"sku":"RP01462-20","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198276296883,"sku":"RP01462-50","price":315.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198276329651,"sku":"RP01462-100","price":504.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_50c636e2-5780-47d4-a4d6-82fe88ba916b.png?v=1766960016","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-fabp4-a-fabp-albp-protein-rp01462","provider":"AFSBio Inc.","version":"1.0","type":"link"}