{"product_id":"recombinant-mouse-fc-gamma-riv-fcgr3a-cd16a-protein-rp01394","title":"Recombinant Mouse Fc-gamma RIV\/FCGR3A\/CD16a Protein - RP01394","description":"\u003cp\u003eRecombinant Mouse Fc-gamma RIV\/FCGR3A\/CD16a Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01394-10, RP01394-20, RP01394-50, RP01394-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Mouse Fc-gamma RIV\/FCGR3A\/CD16a Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly21-Gln 203) of mouse Fc gamma RIV\/CD16-2 (Accession #NP_653142.2) fused with a 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Fc gamma RIV, CD16-2, Fcgr4, FCGR4, mouse igg, FcgR4\u003c\/p\u003e\n\n\u003cp\u003eSWISS: A0A0B4J1G0\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 246256\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: FcgammaRIV is a relatively new IgG Fc receptor (FcgammaR) that is reported to contribute to the pathogenesis of autoimmune diseases.FcgammaRIII and FcgammaRIV are each essential to trigger an FcRgamma-linker for activation of T-cell-dependent signal that drives C5a production in the Arthus reaction. A combined requirement for FcgammaRIII and FcgammaRIV in autoimmune injury, and identify the linker for activation of T cells adaptor as an integral component of linked FcgammaR and C5a anaphylatoxin receptor activation to generate inflammation.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: GLQKAVVNLDPKWVRVLEEDSVTLRCQGTFSPEDNSIKWFHNESLIPHQDANYVIQSARVKDSGMYRCQTALSTISDPVQLEVHMGWLLLQTTKWLFQEGDPIHLRCHSWQNRPVRKVTYLQNGKGKKYFHENSELLIPKATHNDSGSYFCRGLIGHNNKSSASFRISLGDPGSPSMFPPWHQ\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198275838131,"sku":"RP01394-10","price":196.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198275870899,"sku":"RP01394-20","price":266.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198275903667,"sku":"RP01394-50","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198275936435,"sku":"RP01394-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_19fd1afe-4703-493b-aae9-a2fbff2d29b5.png?v=1766960011","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-fc-gamma-riv-fcgr3a-cd16a-protein-rp01394","provider":"AFSBio Inc.","version":"1.0","type":"link"}