{"product_id":"recombinant-mouse-ifn-gamma-protein-rp01070","title":"Recombinant Mouse IFN-gamma Protein - RP01070","description":"\u003cp\u003eRecombinant Mouse IFN-gamma Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20ug, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01070-20, RP01070-50, RP01070-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Mouse IFN-gamma Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Cys155) of mouse Interferon Gamma (Accession #NP_032363.1) fused with an Fc, 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: IFG, IFI, IFN gamma, Interferon Gamma, IFNG\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P01580\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 15978\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 90 % as determined by SDS-PAGE; ≥ 90 % as determined by HPLC.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Interferon-gamma (IFN-gamma ) is a secreted protein which belongs to the type II interferon family. IFN-gamma is produced by a variety of immune cells under inflammatory conditions, notably by T cells and NK cells. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. Interferon-gamma is a central regulator of the immune response and signals via the Janus Activated Kinase (JAK)-Signal Transducer and Activator of Transcription (STAT) pathway.\u003c\/p\u003e\n\n\u003cp\u003eBio-Activity: 1.Measured by its binding ability in a functional ELISA. Immobilized recombinant Mouse IFNGR1 at 0.2 μg\/mL (100 μL\/well) can bind recombinant Mouse IFNG, the EC50 of Mouse IFNG is 2.2 ng\/mL.|2.M0 macrophages(Catalog # RP01216S) can be induced differentiation into M1 macrophages(CD86+CD206-) by Recombinant Mouse IFN-gamma Protein (50ng\/mL) and LPS (100ng\/mL).\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-hFc\u0026amp;His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: MNATHCILALQLFLMAVSGCYCHGTVIESLESLNNYFNSSGIDVEEKSLFLDIWRNWQKDGDMKILQSQIISFYLRLFEVLKDNQAISNNISVIESHLITTFFSNSKAKKDAFMSIAKFEVNNPQVQRQAFNELIRVVHQLLPESSLRKRKRSRC\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20ug","offer_id":45198384398515,"sku":"RP01070-20","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198384431283,"sku":"RP01070-50","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198384464051,"sku":"RP01070-100","price":336.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_58f384e8-cf18-4492-a78b-f904b8f372ed.png?v=1766961521","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-ifn-gamma-protein-rp01070","provider":"AFSBio Inc.","version":"1.0","type":"link"}