{"product_id":"recombinant-mouse-il-17ra-cd217-protein-rp01592","title":"Recombinant Mouse IL-17RA\/CD217 Protein - RP01592","description":"\u003cp\u003eRecombinant Mouse IL-17RA\/CD217 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01592-10, RP01592-20, RP01592-50, RP01592-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Mouse IL-17RA\/CD217 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ser32-Trp322) of mouse IL-17RA\/CD217 (Accession #NP_032385.1) fused with a hFc tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: CANDF5 , CD217 , CDw217 , hIL-17R , IL-17RA , IL17R, IL17RA\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q60943\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 16172\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. This transmembrane protein (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure.\u003c\/p\u003e\n\n\u003cp\u003eBio-Activity: Measured by its binding ability in a functional ELISA. Immobilized Mouse IL-17A\/CTLA-8 at 2 μg\/mL (100 μL\/well) can bind Mouse IL-17RA\/CD217 with a linear range of 0.1-26 ng\/mL.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-hFc\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: SPRLLDFPAPVCAQEGLSCRVKNSTCLDDSWIHPKNLTPSSPKNIYINLSVSSTQHGELVPVLHVEWTLQTDASILYLEGAELSVLQLNTNERLCVKFQFLSMLQHHRKRWRFSFSHFVVDPGQEYEVTVHHLPKPIPDGDPNHKSKIIFVPDCEDSKMKMTTSCVSSGSLWDPNITVETLDTQHLRVDFTLWNESTPYQVLLESFSDSENHSCFDVVKQIFAPRQEEFHQRANVTFTLSKFHWCCHHHVQVQPFFSSCLNDCLRHAVTVPCPVISNTTVPKPVADYIPLW\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198336753843,"sku":"RP01592-10","price":182.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198336786611,"sku":"RP01592-20","price":217.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198336819379,"sku":"RP01592-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198336852147,"sku":"RP01592-100","price":420.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_f0902f06-be33-4644-a8c8-7281b80cbe60.png?v=1766960749","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-il-17ra-cd217-protein-rp01592","provider":"AFSBio Inc.","version":"1.0","type":"link"}