{"product_id":"recombinant-mouse-il-33-protein-rp00618","title":"Recombinant Mouse IL-33 Protein - RP00618","description":"\u003cp\u003eRecombinant Mouse IL-33 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP00618-10, RP00618-20, RP00618-50, RP00618-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Mouse IL-33 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Ser109-Ile266) of mouse IL-33 (Accession #Q8BVZ5) fused with an initial Met at the N-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Il33, Il1f11, NF-HEV, 9230117N10Rik, IL-33\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q8BVZ5\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 77125\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Mouse Interleukin 33 (IL-33) is a proinflammatory cytokine which may also regulates gene transcription inproducer cells. IL-33 is structurally related to IL-1, which induces helper T cells to produce type 2 cytokines andacts through the receptor IL1RL-1. BindingIL-33 to this receptor activates NF-kappa-B and MAP kinases andinduces in vitro Th2 cells to produce cytokines. In vivo, IL-33 induces the expression of IL-4, IL-5, IL-13 and alsoleads to severe pathological changes in mucosal organs.\u003c\/p\u003e\n\n\u003cp\u003eBio-Activity: Measured in a cell proliferation assay using D10.G4.1 mouse helper T cells. The ED50 for this effect is 0.0745-0.298 ng\/mL, corresponding to a specific activity of 3.36×10^6 ~1.34×10^7 units\/mg.\u003c\/p\u003e\n\n\u003cp\u003eSource: E. coli\u003c\/p\u003e\n\n\u003cp\u003eTag: No tag\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μM filtered solution of 20mM PB,150mM NaCl,pH7.4Contact us for customized product form or formulation.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: SIQGTSLLTQSPASLSTYNDQSVSFVLENGCYVINVDDSGKDQEQDQVLLRYYESPCPASQSGDGVDGKKLMVNMSPIKDTDIWLHANDKDYSVELQRGDVSPPEQAFFVLHKKSSDFVSFECKNLPGTYIGVKDNQLALVEEKDESCNNIMFKLSKI\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198305984691,"sku":"RP00618-10","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198306017459,"sku":"RP00618-20","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198306050227,"sku":"RP00618-50","price":350.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198306082995,"sku":"RP00618-100","price":560.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_30219005-b2d2-43b2-8e6a-8987782bda8b.png?v=1766960394","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-il-33-protein-rp00618","provider":"AFSBio Inc.","version":"1.0","type":"link"}