{"product_id":"recombinant-mouse-il-36-gamma-il-1f9-protein-rp01762","title":"Recombinant Mouse IL-36 gamma\/IL-1F9 Protein - RP01762","description":"\u003cp\u003eRecombinant Mouse IL-36 gamma\/IL-1F9 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01762-10, RP01762-20, RP01762-50, RP01762-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Mouse IL-36 gamma\/IL-1F9 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly13-Ser164) of mouse IL36G (Accession #) fused with and a 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: If36g; Il1f9; IL-36gamma\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q8R460\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 215257\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein is a member of the interleukin 1 cytokine family. The activity of this cytokine is mediated by interleukin 1 receptor-like 2 (IL1RL2\/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5\/IL-1 delta). Interferon-gamma, tumor necrosis factor-alpha and interleukin 1, beta (IL1B) are reported to stimulate the expression of this cytokine in keratinocytes. The expression of this cytokine in keratinocytes can also be induced by a contact hypersensitivity reaction or herpes simplex virus infection.\u003c\/p\u003e\n\n\u003cp\u003eBio-Activity: Measured by its ability to induce IL-6 secretion by NIH‑3T3 mouse embryonic fibroblast cells. Towne, J.E. et al. (2004) J. Biol. Chem. 279:13677. The ED5 for this effect is 0.1-0.4 μg\/mL,corresponding to a specific activity of 2.5×10^3 ~1×10^4 units\/mg.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: GRETPDFGEVFDLDQQVWIFRNQALVTVPRSHRVTPVSVTILPCKYPESLEQDKGIAIYLGIQNPDKCLFCKEVNGHPTLLLKEEKILDLYHHPEPMKPFLFYHTRTGGTSTFESVAFPGHYIASSKTGNPIFLTSKKGEYYNINFNLDIKS\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.01 EU\/μg of the protein by LAL method\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198336884915,"sku":"RP01762-10","price":168.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198336917683,"sku":"RP01762-20","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198336950451,"sku":"RP01762-50","price":420.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198336983219,"sku":"RP01762-100","price":672.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_031940dd-9dfa-4484-9a1b-f868ef6857d5.png?v=1766960751","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-il-36-gamma-il-1f9-protein-rp01762","provider":"AFSBio Inc.","version":"1.0","type":"link"}