{"product_id":"recombinant-mouse-il-7-protein-rp01766","title":"Recombinant Mouse IL-7 Protein - RP01766","description":"\u003cp\u003eRecombinant Mouse IL-7 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01766-10, RP01766-20, RP01766-50, RP01766-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Mouse IL-7 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu26-Ile154) of mouse IL-7 (Accession #NP_032397.1) fused with a 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Il-7; hlb368; A630026I06Rik; il7\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P10168\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 16196\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 90 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: IL7, also known as interleukin 7, is a hematopoietic growth factor that belongs to the IL-7\/IL-9 family. It is secreted by stromal cells in the bone marrow and thymus. IL7 stimulates the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. IL7 and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. It is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCR?) during early T cell development. IL7 can be produced locally by intestinal epithelial and epithelial goblet cells and may serve as a regulatory factor for intestinal mucosal lymphocytes.\u003c\/p\u003e\n\n\u003cp\u003eBio-Activity: Measured in a cell proliferation assay using murine 2E8 cells. The ED50 for this effect is 1.1-4.2 ng\/mL, corresponding to a specific activity of 2.38×10^5 ~9.1×10^5 units\/mg.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: ECHIKDKEGKAYESVLMISIDELDKMTGTDSNCPNNEPNFFRKHVCDDTKEAAFLNRAARKLKQFLKMNISEEFNVHLLTVSQGTQTLVNCTSKEEKNVKEQKKNDACFLKRLLREIKTCWNKILKGSI\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.01 EU\/μg of the protein by LAL method\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198347862195,"sku":"RP01766-10","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198347894963,"sku":"RP01766-20","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198347927731,"sku":"RP01766-50","price":490.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198347960499,"sku":"RP01766-100","price":784.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_a2d7007d-3bc9-4889-a6cc-6fd6677f73ef.png?v=1766960881","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-il-7-protein-rp01766","provider":"AFSBio Inc.","version":"1.0","type":"link"}