{"product_id":"recombinant-mouse-il10-protein-his-tag-pdmm100040","title":"Recombinant Mouse IL10 protein (His tag) - PDMM100040","description":"\u003cp\u003eRecombinant Mouse IL10 protein (His tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μg, 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PDMM100040-20, PDMM100040-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: IL10\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Interleukin-10; Il10; IL-10; Cytokine synthesis inhibitory factor; CSIF;\u003c\/p\u003e \n\n\u003cp\u003eUNIProt ID: P18893\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: immunology; cytokine; cancer\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Mouse\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-His\u003c\/p\u003e\n\n\u003cp\u003eAccession: P18893\u003c\/p\u003e\n\n\u003cp\u003eBackground: Mouse Il10 is the prototypic member of the IL-10 cytokine family, including IL-10, IL-19, IL-20, IL-22 (IL-TIF), IL-24 and IL-26. Many viruses encode viral members of the IL-10 family, such as Epstein-Barr virus (EBV) and human cytomegalovirus (HCMV).Its main function is inhibiting the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. Although human and mouse IL-10 are 81% identical at the nucleotide and amino acid level, mouse IL-10 is species-specific and does not act on human cells. Interestingly, Human IL-10 is active on mouse cells.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met1-178Ser\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Please contact us for more information.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 19.47 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 22 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"20μg","offer_id":43083634966707,"sku":"PDMM100040-20","price":264.6,"currency_code":"CAD","in_stock":true},{"title":"100μg","offer_id":43083634999475,"sku":"PDMM100040-100","price":418.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_2ce2c431-6149-4783-91e6-42c7c21d07c9.png?v=1708945697","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-il10-protein-his-tag-pdmm100040","provider":"AFSBio Inc.","version":"1.0","type":"link"}