{"product_id":"recombinant-mouse-il6-proteinhis-tag-pdmm100008","title":"Recombinant Mouse IL6 protein(His tag) - PDMM100008","description":"\u003cp\u003eRecombinant Mouse IL6 protein(His tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μg, 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PDMM100008-20, PDMM100008-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: IL6\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: IL-6; B-cell hybridoma growth factor; Interleukin HP-1; IL 6\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P08505\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Mouse\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-His\u003c\/p\u003e\n\n\u003cp\u003eAccession: P08505\u003c\/p\u003e\n\n\u003cp\u003eBackground: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism (Probable). Binds to IL6R, then the complex associates to the signaling subunit IL6ST\/gp130 to trigger the intracellular IL6-signaling pathway.The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met1-Thr211\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Please contact us for more information.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 23 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 25-30 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"20μg","offer_id":43149108609203,"sku":"PDMM100008-20","price":264.6,"currency_code":"CAD","in_stock":true},{"title":"100μg","offer_id":43149108641971,"sku":"PDMM100008-100","price":418.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_00f590eb-8da2-4f3d-a951-d17266322551.png?v=1710340751","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-il6-proteinhis-tag-pdmm100008","provider":"AFSBio Inc.","version":"1.0","type":"link"}