{"product_id":"recombinant-mouse-interleukin-2-il-2-protein-active-pksm041320","title":"Recombinant Mouse Interleukin-2\/IL-2 Protein (Active) - PKSM041320","description":"\u003cp\u003eRecombinant Mouse Interleukin-2\/IL-2 Protein (Active)\u003c\/p\u003e\n\n\u003cp\u003eSize: 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: PKSM041320-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Interleukin-2; IL-2\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: IL2; Aldesleukin; Interleukin 2; Interleukin-2; IL-2; IL2; T-cell growth facter; T cell growth factor; TCGF\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Mouse\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eApplication: Cell culture\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: None\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P04351\u003c\/p\u003e\n\n\u003cp\u003eAccession: P04351\u003c\/p\u003e\n\n\u003cp\u003eBackground: Interleukin 2 (IL 2), also termed T-cell growth factor, is a member of the cytokine family which includes IL-4, IL-7, IL-9, IL-15 and IL-21. Each member of this family has a four alpha helix bundle. IL-2 signals through the IL-2 receptor, a complex consisting of tree subunits, termed alpha, beta and gamma. The IL-2 R gamma is shared by cytokine receptors of all members of cytokine family. Mature mouse IL-2 shares 56% and 73% aa sequence identity with human and rat IL-2, respectively. IL-2 is produced by CD4+ T cell, CD8+ T cells, gamma δ T cells, B cells, dendritic cells and eosinophils, and plays a vital role in key function of the immune system, tolerance and immunity, primarily via its potent stimulatory activity for T cells.Thus, IL-2 may be a key cytokine in the natural suppression of autoimmunity.\u003c\/p\u003e\n\n\u003cp\u003eActivity: Measured in a cell proliferation assay using CTLL‑2 mouse cytotoxic T cells. The specific activity of Recombinant Mouse IL-2 is ≥1×107 IU\/mg.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Ala21-Gln169\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 20mM Sodium Citrate, 0.2%Tween 80, pH3.0.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.01 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 17.4 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 17 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"Default Title","offer_id":43104365838515,"sku":"PKSM041320-50","price":441.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_7e1f6747-ebdd-404f-9acd-9249c12ce25d.png?v=1709295294","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-interleukin-2-il-2-protein-active-pksm041320","provider":"AFSBio Inc.","version":"1.0","type":"link"}