{"product_id":"recombinant-mouse-interleukin-36-gamma-il-36-gamma-il-1f9-pksm041397","title":"Recombinant Mouse Interleukin-36 gamma\/IL-36 gamma\/IL-1F9 - PKSM041397","description":"\u003cp\u003eRecombinant Mouse Interleukin-36 gamma\/IL-36 gamma\/IL-1F9\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSM041397-10, PKSM041397-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: IL-36 gamma; IL-1F9\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Interleukin-36 gamma; IL36G; IL-1-related protein 2; IL-1RP2; IL-1 epsilon; IL-1F9; Interleukin-1 homolog 1; IL-1H1\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q8R460\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Mouse\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: None\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q8R460\u003c\/p\u003e\n\n\u003cp\u003eBackground: Interleukin-36 gamma (IL-36γ) is a member of the interleukin 1 cytokine family that includes three closely related genes, IL-36α, β, and γ, formerly known as IL-1F6, F8, and F9 respectively. IL-36α has been detected in both neuronal and synovial tissue, whereas IL-36β and IL-36γ are expressed in both cutaneous and mucosal epithelial cells, including the respiratory tract. IL-36β and IL-36γ stimulate proliferation, maturation and\/or cytokine expression by innate immune cells (such as keratinocytes and dendritic cells), and adaptive immune cells (neutrophils and T-cells) in both humans and mice. The activity of IL-36α is mediated by interleukin 1 receptor-like 2 (IL1RL2\/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5\/IL-1 delta). IL-36γ plays an important role in communicating the cell death to surrounding cells.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Gly13-Ser164\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 1 M MOPS, 10 mM NaAc, 2 mM EDTA, 5 % Trehalose, 0.02 % Tween-20, pH 7.6.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 17.3 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 17 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43072220168371,"sku":"PKSM041397-10","price":414.4,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43072220201139,"sku":"PKSM041397-50","price":1244.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_e48fd45d-5414-45e9-951e-2b8afa77eef9.png?v=1708684407","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-interleukin-36-gamma-il-36-gamma-il-1f9-pksm041397","provider":"AFSBio Inc.","version":"1.0","type":"link"}