{"product_id":"recombinant-mouse-kynu-kynureninase-protein-his-tagactive-pksm040748","title":"Recombinant Mouse KYNU\/Kynureninase Protein (His Tag)(Active) - PKSM040748","description":"\u003cp\u003eRecombinant Mouse KYNU\/Kynureninase Protein (His Tag)(Active)\u003c\/p\u003e\n\n\u003cp\u003eSize: 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: PKSM040748-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: KYNU; Kynureninase\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: 4432411A05Rik\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Mouse\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: Baculovirus-Insect Cells\u003c\/p\u003e\n\n\u003cp\u003eApplication: Enzyme\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9CXF0\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q9CXF0\u003c\/p\u003e\n\n\u003cp\u003eBackground: Genetic studies in mouse and human suggest that kynureninase activity may influence blood pressure and renal function. The gene coding kynureninase (KYNU) is also located on chromosome band 2q14-q23, where a linkage peak for essential hypertension was previously detected in the Chinese Han population.The results show that the rare KYNU variant Arg188Gln affects kynureninase activity and are consistent with the hypothesis that this mutation can predispose to essential hypertension.\u003c\/p\u003e\n\n\u003cp\u003eActivity: Measured by its ability to oxidize 3-hydroxykynurenine. The specific activity is \u0026gt; 100 pmoles\/min\/μg.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met 1-Ser 464\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 94 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile 20mM Tris, 500mM NaCl, 10% glycerol, pH 8.0\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 53.7 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 47 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"Default Title","offer_id":43104363806899,"sku":"PKSM040748-100","price":1197.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_81a990af-e98f-45d6-bbe7-ff2e93f57f20.png?v=1709295249","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-kynu-kynureninase-protein-his-tagactive-pksm040748","provider":"AFSBio Inc.","version":"1.0","type":"link"}