{"product_id":"recombinant-mouse-light-proteinn-hisactive-pksm041487","title":"Recombinant Mouse LIGHT protein(N-His)(active) - PKSM041487","description":"\u003cp\u003eRecombinant Mouse LIGHT protein(N-His)(active)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μg, 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSM041487-20, PKSM041487-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: LIGHT\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: 1700013B14Rik\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Mouse\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eApplication: Cell culture\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9QYH9\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q9QYH9\u003c\/p\u003e\n\n\u003cp\u003eBackground: Cytokine that binds to TNFRSF3\/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB and stimulates the proliferation of T-cells. Acts as a ligand for TNFRSF14\/HVEM. Upon binding to TNFRSF14\/HVEM, delivers costimulatory signals to T cells, leading to T cell proliferation and IFNG production.\u003c\/p\u003e\n\n\u003cp\u003eActivity: Measure by its ability to induce cytotoxicity in HT-29 cells. The ED50 for this effect is \u0026lt; 2 μg\/mL.\u003c\/p\u003e\n\n\u003cp\u003eSequence: MESVVQPSVFVVDGQTDIPFRRLEQNHRRRRCGTVQVSLALVLLLGAGLATQGWFLLRLHQRLGDIVAHLPDGGKGSWEKLIQDQRSHQANPAAHLTGANASLIGIGGPLLWETRLGLAFLRGLTYHDGALVTMEPGYYYVYSKVQLSGVGCPQGLANGLPITHGLYKRTSRYPKELELLVSRRSPCGRANSSRVWWDSSFLGGVVHLEAGEEVVVRVPGNRLVRPRDGTRSYFGAFMV\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 98 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile PBS, pH 7.4\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 27.17 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"20μg","offer_id":43118181810355,"sku":"PKSM041487-20","price":348.6,"currency_code":"CAD","in_stock":true},{"title":"100μg","offer_id":43118181843123,"sku":"PKSM041487-100","price":1034.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_fa3fbaa3-6915-43cb-afce-1ab15ff3caee.png?v=1709637650","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-light-proteinn-hisactive-pksm041487","provider":"AFSBio Inc.","version":"1.0","type":"link"}