{"product_id":"recombinant-mouse-m-csf-csf1-protein-his-tag-pksm041110","title":"Recombinant Mouse M-CSF\/CSF1 Protein (His Tag) - PKSM041110","description":"\u003cp\u003eRecombinant Mouse M-CSF\/CSF1 Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSM041110-10, PKSM041110-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: M-CSF; CSF1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Macrophage colony-stimulating factor 1; CSF-1; MCSF; Csf1; Csfm\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P07141\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Mouse\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: P07141\u003c\/p\u003e\n\n\u003cp\u003eBackground: Macrophage colony-stimulating factor 1（M-csf）is a single-pass type I membrane protein. It is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte\/macrophage cell lineage. By interacting with its membrane receptor, M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Lys33-Glu262\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 27.0 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 43 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43072200245427,"sku":"PKSM041110-10","price":249.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43072200278195,"sku":"PKSM041110-50","price":732.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_1f343be9-2b32-4ccf-a5d8-c2041a06dcbc.png?v=1708683805","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-m-csf-csf1-protein-his-tag-pksm041110","provider":"AFSBio Inc.","version":"1.0","type":"link"}