{"product_id":"recombinant-mouse-m-csf-proteinn-hisactive-pksm041498","title":"Recombinant Mouse M-CSF protein(N-His)(active) - PKSM041498","description":"Recombinant Mouse M-CSF protein(N-His)(active)\n\nSizes: 20μg, 100μg\n\nCatalogue Numbers: PKSM041498-20, PKSM041498-100\n\nCitations, Manuals and MSDS Available upon request.\n\nAbbreviation: M-CSF\n\nTarget Symptom: TNFSF4; Ath; Ath-; Ath-1; Ath1; CD134; CD134L; OX-40L; OX4; TXGP1; Tnlg2b; Txgp; Txgp1l; gp3; gp34\n\nTarget Species: Mouse\n\nExpression Host: E.coli\n\nApplication: Cell culture\n\nFusion Tag: C-His\n\nUNIProt ID: P07141\n\nAccession: P07141\n\nBackground: Macrophage colony-stimulating factor 1（M-csf）is a single-pass type I membrane protein . It is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte\/macrophage cell lineage. By interacting with its membrane receptor, M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.\n\nActivity: Measure by its ability to induce proliferation in NFS-60 cells. The ED50 for this effect is \u0026lt; 2 ng\/mL. The specific activity of recombinant mouse M-CSF is approximately \u0026gt; 5 x 10\u003csup\u003e5\u003c\/sup\u003eIU\/mg.\n\nSequence: Lys32-Pro187\n\nPurity: \u0026gt; 98 % as determined by reducing SDS-PAGE.\n\nFormulation: Lyophilized from sterile PBS, pH 8.0\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\nPlease refer to the specific buffer information in the printed manual.\n\nReconstitution: Please refer to the printed manual for detailed information.\n\nEndotoxin: \u0026lt; 0.1 EU per μg of the protein as determined by the LAL method.\n\nCalculated MW: 19 kDa\n\nStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\n\nShipping: This product is provided as lyophilized powder which is shipped with ice packs.\n\nResearch Use Only","brand":"Elabscience","offers":[{"title":"20μg","offer_id":43118183219379,"sku":"PKSM041498-20","price":348.6,"currency_code":"CAD","in_stock":true},{"title":"100μg","offer_id":43118183252147,"sku":"PKSM041498-100","price":1034.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_dddf19c8-359b-4112-995d-6d628dc0198c.png?v=1709637688","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-m-csf-proteinn-hisactive-pksm041498","provider":"AFSBio Inc.","version":"1.0","type":"link"}