{"product_id":"recombinant-mouse-msr1-cd204-protein-rp01843","title":"Recombinant Mouse MSR1\/CD204 Protein - RP01843","description":"\u003cp\u003eRecombinant Mouse MSR1\/CD204 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01843-10, RP01843-20, RP01843-50, RP01843-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Mouse MSR1\/CD204 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Trp83-Val354) of Mouse MSR1\/CD204 (Accession #NP_001106797.1) fused with a His tag at the N-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Macrophage scavenger receptor types I and II, Macrophage acetylated LDL receptor I and II, Scavenger receptor type A, SR-A, CD204, Msr1, Scvr\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P30204\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 20288\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Macrophage scavenger receptor 1 (MSR1) is also known as CD204, SCARA1, SR-A, and is class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. Defects in MSR1 may be a cause of prostate cancer (PC) or Barrett esophagus (BE).\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: N-His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: WEMKNCLVCSLNTSDTSQGPMEKENTSKVEMRFTIIMEHMKDMEERIESISNSKADLIDTERFQNFSMATDQRLNDILLQLNSLISSVQEHGNSLDAISKSLQSLNMTLLDVQLHTETLNVRVRESTAKQQEDISKLEERVYKVSAEVQSVKEEQAHVEQEVKQEVRVLNNITNDLRLKDWEHSQTLKNITFIQGPPGPQGEKGDRGLTGQTGPPGAPGIRGIPGVKGDRGQIGFPGGRGNPGAPGKPGRSGSPGPKGQKGEKGSVGGSTPL\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198261616819,"sku":"RP01843-10","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198261649587,"sku":"RP01843-20","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198261682355,"sku":"RP01843-50","price":350.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198261715123,"sku":"RP01843-100","price":504.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_d0a1c26e-2c2c-49e4-82e5-94db70e50fe4.png?v=1766959855","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-msr1-cd204-protein-rp01843","provider":"AFSBio Inc.","version":"1.0","type":"link"}