{"product_id":"recombinant-mouse-mydgf-protein-rp01822","title":"Recombinant Mouse MYDGF Protein - RP01822","description":"\u003cp\u003eRecombinant Mouse MYDGF Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01822-10, RP01822-20, RP01822-50, RP01822-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Mouse MYDGF Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val25-Leu166) of mouse MYDGF (Accession #NP_543027.1) fused with a 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Mydgf, Myeloid-derived growth factor, MYDGF\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q9CPT4\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 28106\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Myeloid-derived growth factor (MYDGF) is a secreted protein which belongs to the UPF0556 family. MYDGF was strongly expressed in spleen, prostate and lung, and weakly expressed in the left ventricle and liver. Bone marrow-derived monocyte and paracrine-acting protein promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and\/or repair after myocardial infarction (MI). MYDGF stimulates endothelial cell proliferation through a MAPK1\/3-, STAT3- and CCND1-mediated signaling pathway. It inhibits cardiac myocyte apoptosis in a PI3K\/AKT-dependent signaling pathway. MYDGF is involved in endothelial cell proliferation and angiogenesis. It may serve as a prototypical example for the development of protein-based therapies for ischemic tissue repair.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: VSEPTTVPFDVRPGGVVHSFSQDVGPGNKFTCTFTYASQGGTNEQWQMSLGTSEDSQHFTCTIWRPQGKSYLYFTQFKAELRGAEIEYAMAYSKAAFERESDVPLKSEEFEVTKTAVSHRPGAFKAELSKLVIVAKAARSEL\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.01 EU\/μg of the protein by LAL method\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198270955699,"sku":"RP01822-10","price":168.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198270988467,"sku":"RP01822-20","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198271021235,"sku":"RP01822-50","price":420.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198271054003,"sku":"RP01822-100","price":672.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_492220ac-59a2-49a6-b6b3-9b0617a09ad2.png?v=1766959955","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-mydgf-protein-rp01822","provider":"AFSBio Inc.","version":"1.0","type":"link"}