{"product_id":"recombinant-mouse-neurotrophic-tyrosine-kinase-receptor-type-2-trkb-ntrk2-c-6his-pksm041430","title":"Recombinant Mouse Neurotrophic Tyrosine Kinase Receptor Type 2\/TrkB\/NTRK2 (C-6His) - PKSM041430","description":"\u003cp\u003eRecombinant Mouse Neurotrophic Tyrosine Kinase Receptor Type 2\/TrkB\/NTRK2 (C-6His)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSM041430-10, PKSM041430-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: TrkB; NTRK2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: BDNF\/NT-3 Growth Factors Receptor; GP145-TrkB; Trk-B; Neurotrophic Tyrosine Kinase Receptor Type 2; TrkB Tyrosine Kinase; Tropomyosin-Related Kinase B; NTRK2; TRKB\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P15209\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Mouse\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: P15209\u003c\/p\u003e\n\n\u003cp\u003eBackground: The TRK Family of Tyrosine Kinase Receptor consists of 3 members: TrkA, TrkB and TrkC. The three TRK family proteins have different ligand specificities. They connect to different neurotrophins, including NGF, BDNF, NT-3NT-4\/5. TRKA binds NGF, TRKB binds BDNF and NT-3, TRKC binds NT-4\/5. At the protein sequence level, human and rat TRKB have greater than 90% sequence identity and the proteins exbihit cross-species activity. TRKB is primarily expressed in the nervous system and it also expression in a wide variety of tissues with low levels.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Cys32-His429\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 45.3 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 60-90 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43072223150259,"sku":"PKSM041430-10","price":378.0,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43072223183027,"sku":"PKSM041430-50","price":1131.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_4110823a-2794-4e88-91da-a895d6ab39e3.png?v=1708684522","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-neurotrophic-tyrosine-kinase-receptor-type-2-trkb-ntrk2-c-6his-pksm041430","provider":"AFSBio Inc.","version":"1.0","type":"link"}