{"product_id":"recombinant-mouse-ngf-ngfb-beta-ngf-protein-his-tag-pdem100106","title":"Recombinant Mouse NGF\/NGFB\/beta-NGF protein (His tag) - PDEM100106","description":"\u003cp\u003eRecombinant Mouse NGF\/NGFB\/beta-NGF protein (His tag)\u003c\/p\u003e\n\n\u003cp\u003eSize: 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PDEM100106-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: NGF; NGFB; beta-NGF\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Beta-Nerve Growth Factor; Beta-NGF; NGF; NGFB\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P01139\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer; \u003cbr\u003e\nCell Biology; Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Mouse\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-His\u003c\/p\u003e\n\n\u003cp\u003eAccession: P01139\u003c\/p\u003e\n\n\u003cp\u003eBackground: NGF is the first member discovered in the Neurotrophin family, which includes brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4). These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Mouse beta -NGF is a homodimer of two 120 amino acid polypeptides. It shares approximately 90% homology at the amino acid level with human beta -NGF and 95.8% with rat beta -NGF. NGF signaling has been shown to play an important role in neuroprotection and repair. β-NGF acts as a growth and differentiation factor for B lymphocytes, and enhances B-cell survival. It is a potent neurotrophic factor that signals through its receptor β-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Ser 122-Gly 241\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Please contact us for more information.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 13.09 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 15 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"100μg","offer_id":43083597185203,"sku":"PDEM100106-100","price":165.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_0ca4280e-9594-4f4d-9906-bb369780dc7e.png?v=1708944955","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-ngf-ngfb-beta-ngf-protein-his-tag-pdem100106","provider":"AFSBio Inc.","version":"1.0","type":"link"}