{"product_id":"recombinant-mouse-omgp-omg-protein-aa-1-245-his-tag-pksm040549","title":"Recombinant Mouse OMGP\/OMG Protein (aa 1-245, His Tag) - PKSM040549","description":"\u003cp\u003eRecombinant Mouse OMGP\/OMG Protein (aa 1-245, His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSize: 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: PKSM040549-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: OMGP, OMG\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: RP23-67E18.6, LNGFR, Tnfrsf16, p75, p75NGFR, p75NTR\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q63912\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Mouse\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-His\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q63912\u003c\/p\u003e\n\n\u003cp\u003eBackground: Oligodendrocyte-myelin glycoprotein, also known as OMG and OMGP, is a cell membrane protein which contains eightLRR (leucine-rich) repeats. OMG \/ OMGP is a glycosylphosphatidylinositol-anchored protein expressed by neurons and oligodendrocytes in the central nervous system (CNS). OMG \/ OMGP is a cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system. OMG \/ OMGP play roles in both the developing and adult central nervous system. OMG \/ OMGP participats in growth cone collapse and inhibition of neurite outgrowth through its interaction with NgR, the receptor for Nogo. This function requires its leucine-rich repeat domain, a highly conserved region in OMgp during mammal evolution. OMG \/ OMGP leucine-rich repeat domain is also implicated in the inhibition of cell proliferation. OMG \/ OMGP may also be involved in the formation and maintenance of myelin sheaths. Cell proliferation, neuronal sprouting and myelination are crucial processes involved in brain development and regeneration after injury.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met 1-Thr 245\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile PBS, pH 7.4\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 27 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 44 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"50μg","offer_id":43155010093235,"sku":"PKSM040549-50","price":1024.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_a421443e-0c8e-4681-bba1-9b3f165e6928.png?v=1710436207","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-omgp-omg-protein-aa-1-245-his-tag-pksm040549","provider":"AFSBio Inc.","version":"1.0","type":"link"}