{"product_id":"recombinant-mouse-pentraxin-related-protein-ptx3n-6his-pksm041439","title":"Recombinant Mouse Pentraxin-related protein PTX3(N-6His) - PKSM041439","description":"\u003cp\u003eRecombinant Mouse Pentraxin-related protein PTX3(N-6His)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSM041439-10, PKSM041439-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Pentraxin-relatedPTX3\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: alpha-induced protein 5; pentaxin-related gene; rapidly induced by IL-1 beta; tumor necrosis factor; Pentaxin-related protein PTX3; Pentraxin 3; pentraxin 3; long; pentraxin-3; pentraxin-related gene; rapidly induced by IL-1 beta; pentraxin-related protein PTX3; PTX3; TNF alpha-induced protein 5; TNFAIP5; TSG14; TSG-14\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P48759\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Mouse\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: P48759\u003c\/p\u003e\n\n\u003cp\u003eBackground: Pentraxin-related protein PTX3, also known as Tumor necrosis factor-inducible gene 14 protein (TSG-14), belongs to the pentraxin family. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. It’s subunit is a disulfide-linked homooctamer that binds to C1q. PTX3 concentration is elevated in the joint fluid of patients with rheumatoid arthritis (RA), indicating that PTX3 may be a potential mediator of immune response. PTX3 may also function in the regulation of the uptake and clearance of apoptotic cells by dendritic cells. An in vivo study showed that PTX3 transgenic mice are more resistant to sepsis and endotoxemia compared to wild-type during inflammatory injury.\u003c\/p\u003e\n\n\u003cp\u003eSequence: His18-Ser381\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 90 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 41 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 54 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43072224002227,"sku":"PKSM041439-10","price":310.8,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43072224034995,"sku":"PKSM041439-50","price":912.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_a83af440-e80b-4567-b929-128d2297a83e.png?v=1708684556","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-pentraxin-related-protein-ptx3n-6his-pksm041439","provider":"AFSBio Inc.","version":"1.0","type":"link"}