{"product_id":"recombinant-mouse-placenta-growth-factor-plgf-pgf-protein-rp01941","title":"Recombinant Mouse Placenta growth factor\/PLGF\/PGF Protein - RP01941","description":"\u003cp\u003eRecombinant Mouse Placenta growth factor\/PLGF\/PGF Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01941-10, RP01941-20, RP01941-50, RP01941-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Mouse Placenta growth factor\/PLGF\/PGF Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala24-Pro158) of Mouse Placenta growth factor\/PLGF\/PGF(Accession #NP_032853.1) fused with a Avi\u0026amp;His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Pgf, Plgf, Placenta growth factor, PlGF\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P49764\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 18654\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Store the lyophilized protein at -20℃ to -80℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Placenta growth factor (PlGF) is a member of the PDGF\/VEGF family of growth factors that share a conserved pattern of eight cysteines. Alternative splicing results in at least three human mature PlGF forms containing 131 (PlGF-1), 152 (PlGF-2), and 203 (PlGF-3) amino acids (aa) respectively. Only PlGF-2 contains a highly basic heparin-binding 21 aa insert at the C-terminus. Human PlGF-1 shares 56%, 55%, 74% and 95% aa identity with the comparable isoform of mouse, rat, canine, and equine PlGF, respectively. PlGF is mainly found as variably glycosylated, secreted, 55-60 kDa disulfide linked homodimers. Mammalian cells expressing PlGF include villous trophoblasts, decidual cells, erythroblasts, keratinocytes, and some endothelial cells. Circulating PlGF increases during pregnancy, reaching a peak in mid-gestation; this increase is attenuated in preeclampsia. However, deletion of PlGF in the mouse does not affect development or reproduction. Postnatally, mice lacking PlGF show impaired angiogenesis in response to ischemia.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-Avi\u0026amp;His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: ALSAGNNSTEVEVVPFNEVWGRSYCRPMEKLVYILDEYPDEVSHIFSPSCVLLSRCSGCCGDEGLHCVPIKTANITMQILKIPPNRDPHFYVEMTFSQDVLCECRPILETTKAERRKTKGKRKRSRNSQTEEPHP\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198267154611,"sku":"RP01941-10","price":168.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198267187379,"sku":"RP01941-20","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198267220147,"sku":"RP01941-50","price":420.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198267252915,"sku":"RP01941-100","price":672.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_d1e4e354-3a1f-4ab0-aa66-11450ba90857.png?v=1766959913","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-placenta-growth-factor-plgf-pgf-protein-rp01941","provider":"AFSBio Inc.","version":"1.0","type":"link"}