{"product_id":"recombinant-mouse-rat-mature-tgf-beta-1-protein-rp00671","title":"Recombinant Mouse\/Rat Mature TGF-beta 1 Protein - RP00671","description":"\u003cp\u003eRecombinant Mouse\/Rat Mature TGF-beta 1 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP00671-10, RP00671-20, RP00671-50, RP00671-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Mouse TGF-beta 1\/TGFB1 Protein is produced by Human cells expression system. The target protein is expressed with sequence (Ala279-Ser390) of mouse TGF-beta 1\/TGFB1 (Accession #P04202).\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: TGF-beta1, Tgfb, Tgfb-1, TGFbeta1, CED, DPD1, LAP, TGFB, TGFbeta, TGFB1\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P04202\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 21803\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factorsand plays a prominent role in a variety of cellular processes, including cell-cycle progression, celldifferentiation,reproductivefunction,development,motility,adhesion,neuronalgrowth,bonemorphogenesis, wound healing, and immune surveillance. TGF- β 1, TGF- β 2 and TGF- β 3 signal via the sameheteromeric receptor complex, consisting of a ligand binding TGF- β receptor type II (T β R-II), and a TGF- βreceptor type I (T β R-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF- βexpression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney,gut, liver, eye, ear, skin, and the nervous system.\u003c\/p\u003e\n\n\u003cp\u003eBio-Activity: Measured by its ability to inhibit the IL-4-dependent proliferation of HT-2 Mouse T cells. The ED50 for this effect is 0.054-0.214 ng\/mL, corresponding to a specific activity of 4.7×10^6 ~1.85×10^7 units\/mg.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: No tag\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 50 mM Glycine,150 mM NaCl, pH3.5. Contact us for customized product form or formulation.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: ALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASASPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.01 EU\/μg of the protein by LAL method\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198307426483,"sku":"RP00671-10","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198307459251,"sku":"RP00671-20","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198307492019,"sku":"RP00671-50","price":490.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198307524787,"sku":"RP00671-100","price":784.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_d940aebc-80f6-44ef-bf2d-83bc8601855f.png?v=1766960417","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-rat-mature-tgf-beta-1-protein-rp00671","provider":"AFSBio Inc.","version":"1.0","type":"link"}