{"product_id":"recombinant-mouse-rat-mature-tgf-beta-2-protein-rp00672","title":"Recombinant Mouse\/Rat Mature TGF-beta 2 Protein - RP00672","description":"\u003cp\u003eRecombinant Mouse\/Rat Mature TGF-beta 2 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP00672-10, RP00672-20, RP00672-50, RP00672-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Mouse TGF-beta 2\/TGFB2 Protein is produced by Human cells expression system. The target protein is expressed with sequence (Ala303-Ser414) of mouse TGF-beta 2\/TGFB2 (Accession #P27090).\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: TGFB2; BSC-1 cell growth inhibitor; Cetermin; Glioblastoma-derived T-cell suppressor factor; G-TSF; MGC116892; Polyergin; TGF-beta2; TGF-beta-2; transforming growth factor beta-2\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P27090\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 21808\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\/Rat\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Transforming growth factor beta 2 (TGF- β 2) is a member of TGF-beta superfamily that shares a characteristiccysteine knot structure. Mice with TGF- β 2 gene deletion show defects in development of cardiac, lung,craniofacial, limb, spinal column, eye, inner ear and urogenital systems. All TGF-β isoforms signal via the sameheteromeric receptor complex, consisting of a ligand binding TGF- β receptor type II (T β R-II), and a TGF- βreceptor type I (T β R-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF- βexpression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney,gut, liver, eye, ear, skin, and the nervous system.\u003c\/p\u003e\n\n\u003cp\u003eBio-Activity: Recombinant Mouse\/Rat Mature TGF-beta 2 Protein inhibit the IL-4-dependent proliferation of HT-2 mouse T cells. The ED50 for this effect is 0.062-0.248 ng\/mL, corresponding to a specific activity of 4.03×106~1.61×107 units\/mg.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: No tag\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 4 mM HCl.Contact us for customized product form or formulation.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: ALDAAYCFRNVQDNCCLRPLYIDFKRDLGWKWIHEPKGYNANFCAGACPYLWSSDTQHTKVLSLYNTINPEASASPCCVSQDLEPLTILYYIGNTPKIEQLSNMIVKSCKCS\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198312439987,"sku":"RP00672-10","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198312472755,"sku":"RP00672-20","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198312505523,"sku":"RP00672-50","price":490.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198312538291,"sku":"RP00672-100","price":784.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_08c87013-fabe-4db7-8967-a85a2132eef9.png?v=1766960473","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-rat-mature-tgf-beta-2-protein-rp00672","provider":"AFSBio Inc.","version":"1.0","type":"link"}