{"product_id":"recombinant-mouse-rat-tgf-beta-1-ept223","title":"Recombinant Mouse\/Rat TGF-beta 1 - EPT223","description":"\u003cp\u003eRecombinant Mouse\/Rat TGF-beta 1\u003c\/p\u003e\n\n\u003cp\u003eSize: 50ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: EPT223-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differentiation, reproductive function, development, motility, adhesion, neuronal growth, bone morphogenesis, wound healing, and immune surveillance. TGF-β1, TGF-β2 and TGF-β3 signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.\u003c\/p\u003e \n\n\u003cp\u003eAlternate Names: TGF-beta-1; TGFB; TGF-b1; TGFB1; CEDLAP;latency-associated peptide; TGFbeta; TGF-beta 1 protein; transforming growth factor beta-1\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Mouse\/Rat Transforming Growth Factor Beta 1 is produced by our Mammalian expression system and the target gene encoding Ala279-Ser390 is expressed.\u003c\/p\u003e\n\n\u003cp\u003eAccession: P04202\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 12.8 KDa\u003c\/p\u003e\n\n\u003cp\u003eApparent Molecular Weight: 13 KDa, reducing conditions\u003c\/p\u003e\n\n\u003cp\u003eStorage Condition: Lyophilized protein should be stored at \u0026lt; -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20°C for 3 months.\u003c\/p\u003e\n\n\u003cp\u003ePurity: Greater than 95% as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 0.001 ng\/µg (0.01 EU\/µg) as determined by LAL test.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: Immobilized Mouse\/Rat TGF-beta 1 (Cat#CK33) at 2μg\/ml (100 μl\/well) can bind Mouse TGFBR2-His (Cat#CM05).The ED50 of Mouse TGFBR2-His (Cat#CM05)is 2.5 ug\/ml.\u003c\/p\u003e\n\n\u003cp\u003eRedissolve: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg\/ml. Dissolve the lyophilized protein in 4mM HCl. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. \u003c\/p\u003e\n\n\u003cp\u003eDelivery Condition: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Lyophilized protein should be stored at \u0026lt; -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20°C for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"Default Title","offer_id":43211046420659,"sku":"EPT223-50","price":1146.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_a5eeb6b3-4f8f-4e12-b6bb-04446a04f233.png?v=1767117906","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-rat-tgf-beta-1-ept223","provider":"AFSBio Inc.","version":"1.0","type":"link"}