{"product_id":"recombinant-mouse-sclerostin-sost-protein-rp02845","title":"Recombinant Mouse Sclerostin\/SOST Protein - RP02845","description":"\u003cp\u003eRecombinant Mouse Sclerostin\/SOST Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP02845-10, RP02845-50, RP02845-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Mouse Sclerostin\/SOST Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln24-Tyr211) of mouse Sclerostin\/SOST (Accession #NP_077769.4) fused with a His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: SOST, CDD, DAND6, SOST1, VBCH\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q99P68\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 74499\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: QGWQAFRNDATEVIPGLGEYPEPPPENNQTMNRAENGGRPPHHPYDAKDVSEYSCRELHYTRFLTDGPCRSAKPVTELVCSGQCGPARLLPNAIGRVKWWRPNGPDFRCIPDRYRAQRVQLLCPGGAAPRSRKVRLVASCKCKRLTRFHNQSELKDFGPETARPQKGRKPRPGARGAKANQAELENAY\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198373126323,"sku":"RP02845-10","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198373159091,"sku":"RP02845-50","price":490.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198373191859,"sku":"RP02845-100","price":784.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_2e8414ce-b247-43f2-a8f8-ed08a151be44.png?v=1766961361","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-sclerostin-sost-protein-rp02845","provider":"AFSBio Inc.","version":"1.0","type":"link"}