{"product_id":"recombinant-mouse-st6galnac2-protein-his-tag-pksm041361","title":"Recombinant Mouse ST6GALNAC2 Protein (His Tag) - PKSM041361","description":"\u003cp\u003eRecombinant Mouse ST6GALNAC2 Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSM041361-10, PKSM041361-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: ST6GALNAC2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Gal-beta-1; 3-GalNAc alpha-2; 6-sialyltransferase; GalNAc alpha-2; 6-sialyltransferase II; ST6GalNAc II; Sialyltransferase 7B; SIAT7-B; II; Siat7; Siat7b; ST6GalNAc\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P70277\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Mouse\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-His\u003c\/p\u003e\n\n\u003cp\u003eAccession: P70277\u003c\/p\u003e\n\n\u003cp\u003eBackground: Alpha-N-acetylgalactosaminide alpha -2, 6-sialyltransferase 2, is a type-II membrane protein localized in the Golgi network and catalyzes 2, 6-sialylation of the Tn antigen. Sialyl-Tn antigen is highly expressed in several human carcinomas and is associated with carcinoma aggressiveness and poor prognosis.-it has been reported that disregulation of this gene is involved in the pathogenesis of IgA nephropathy, a common kidney disease that occurs when antibody IgA accumulates in kidneys (4). The enzyme may also be used to synthesize a cancer vaccine.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Ser28-Arg373\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 50mMTris, 150mMNaCl, pH7.5.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 40.4 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 45 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43072217055411,"sku":"PKSM041361-10","price":385.0,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43072217088179,"sku":"PKSM041361-50","price":735.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_54406888-2892-4a53-99d1-5c82a652e549.png?v=1708684344","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-st6galnac2-protein-his-tag-pksm041361","provider":"AFSBio Inc.","version":"1.0","type":"link"}