{"product_id":"recombinant-mouse-testican-3-spock3-protein-his-tag-pksm041154","title":"Recombinant Mouse Testican-3\/SPOCK3 Protein (His Tag) - PKSM041154","description":"\u003cp\u003eRecombinant Mouse Testican-3\/SPOCK3 Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSM041154-10, PKSM041154-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Testican-3; SPOCK3\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Testican-3; Spock3\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q8BKV0\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Mouse\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q8BKV0-1\u003c\/p\u003e\n\n\u003cp\u003eBackground: Testican3, also called SPOCK3, is a secreted protein and make up a family of extracellular heparan\/chondroitin sulfate proteoglycans. It contains 1 Kazal-like domain and 1 thyroglobulin type-1 domain. Testican3 contain inhibitory regions in several domains targeted to different classes of protease, and in some cases may act as protease inhibitors. In addition to their presence in testis, testicans are enriched in brain and have been shown to regulate neuronal attachment and outgrowth. It may participate in diverse steps of neurogenesis and Inhibits the processing of pro-matrix metalloproteinase 2 (MMP-2) by MT1-MMP and MT3-MMP. It also may interfere with tumor invasion.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Ala23-Ile436\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 47.9 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 58-60 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43072205357235,"sku":"PKSM041154-10","price":163.8,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43072205390003,"sku":"PKSM041154-50","price":415.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_156dcf13-b82d-40d2-bc59-5603cf1dba44.png?v=1708683915","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-testican-3-spock3-protein-his-tag-pksm041154","provider":"AFSBio Inc.","version":"1.0","type":"link"}