{"product_id":"recombinant-mouse-tnfrsf6-fas-cd95-protein-rp00737","title":"Recombinant Mouse TNFRSF6\/FAS\/CD95 Protein - RP00737","description":"\u003cp\u003eRecombinant Mouse TNFRSF6\/FAS\/CD95 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 50ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: RP00737-10, RP00737-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Mouse TNFRSF6\/FAS\/CD95 Protein is produced by Human Cells expression system. The target protein is expressed with sequence (Gln22-Arg169) of Mouse TNFRSF6\/FAS\/CD95 (Accession #P25446 ) fused with a 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; Apoptosis-mediatingsurface antigen FAS; FASLG receptor; CD95; Fas; TNFRSF6\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P25446\u003c\/p\u003e \n\n\u003cp\u003eGeneID: 14102\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Mouse Apoptosis-mediating surface antigen FAS (Fas) belongs to the death receptor subfamily of the TNFreceptor superfamily and is designated TNFRSF6. Mouse Fas contains 1 death domain and 3 TNFR-Cys repeats.It detected in various tissues including thymus, liver, lung, heart, and adult ovary. As a receptor forTNFSF6\/FASLG, The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequentcascade of caspases mediating apoptosis. FAS-mediated apoptosis may have a role in the induction ofperipheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-6×His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. Contact us for customized product form or formulation.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: QGTNSISESLKLRRRVRETDKNCSEGLYQGGPFCCQPCQPGKKKVEDCKMNGGTPTCAPCTEGKEYMDKNHYADKCRRCTLCDEEHGLEVETNCTLTQNTKCKCKPDFYCDSPGCEHCVRCASCEHGTLEPCTATSNTNCRKQSPRNR\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198353629363,"sku":"RP00737-10","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198353662131,"sku":"RP00737-50","price":420.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_a1b2d8a7-5518-4193-8dc8-7ea31e8bed0b.png?v=1766960996","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-tnfrsf6-fas-cd95-protein-rp00737","provider":"AFSBio Inc.","version":"1.0","type":"link"}