{"product_id":"recombinant-mouse-tnfsf13-april-cd256-protein-rp01753","title":"Recombinant Mouse TNFSF13\/APRIL\/CD256 Protein - RP01753","description":"\u003cp\u003eRecombinant Mouse TNFSF13\/APRIL\/CD256 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01753-10, RP01753-20, RP01753-50, RP01753-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Mouse TNFSF13\/APRIL\/CD256 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Lys104-Leu241) of mouse TNFSF13\/APRIL\/CD256 (Accession #NP_001152977.1) fused with a hFc tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: April; Tall2; Trdl1; Tnlg7b; 2310026N09Rik; TNFSF13; CD256\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q9D777\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 69583\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: TNFSF13 is a member of the tumor necrosis factor (TNF) ligand family. It is a ligand for TNFRSF17\/BCMA. TNFSF13 is lowly expressed in normal tissues, but is elevated in several types of tumors and transformed cell lines. It is important for B cell development. TNFSF13 may also play a role in T-independent type II antigen responses and T cell survival, and induce proliferation\/survival of non lymphoid cells. It exists as a functional homotrimer. It can bind to two cell surface receptors, BCMA and TACI, which it shares with BAFF to exert downstream T- and B-cell regulatory effects. TNFSF13 also has been demonstrated to bind to proteoglycans on the cell surface.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-hFc\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: KKHSVLHLVPVNITSKADSDVTEVMWQPVLRRGRGLEAQGDIVRVWDTGIYLLYSQVLFHDVTFTMGQVVSREGQGRRETLFRCIRSMPSDPDRAYNSCYSAGVFHLHQGDIITVKIPRANAKLSLSPHGTFLGFVKL\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198264762547,"sku":"RP01753-10","price":196.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198264795315,"sku":"RP01753-20","price":266.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198264828083,"sku":"RP01753-50","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198264860851,"sku":"RP01753-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_2b5e6c27-4bc2-4164-ac02-623b920c67d7.png?v=1766959889","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-tnfsf13-april-cd256-protein-rp01753","provider":"AFSBio Inc.","version":"1.0","type":"link"}