{"product_id":"recombinant-mouse-trop2-tacstd2-protein-his-tag-pksm041262","title":"Recombinant Mouse TROP2\/TACSTD2 Protein (His Tag) - PKSM041262","description":"\u003cp\u003eRecombinant Mouse TROP2\/TACSTD2 Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSize: 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: PKSM041262-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: TROP2; TACSTD2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Tumor-associated calcium signal transducer 2; Tacstd2; Trop2; Cell surface glycoprotein Trop-2; TROP-2; C80403; EGP-1; GA733-1; Ly97\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q8BGV3\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Mouse\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-His\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q8BGV3\u003c\/p\u003e\n\n\u003cp\u003eBackground: Tumor-associated calcium signal transducer 2(Tacstd2), also known as Cell surface glycoprotein Trop-2, belongs to the EPCAM family. Tacstd2 expressed in kidney, lung, ovary and testis and has high levels of expression in immortalized keratinocytes. Tacstd2 may functions as a growth factor receptor. It has negative regulation of branching involved in ureteric bud morphogenesis, cell motility, epithelial cell migration, ruffle assembly, stress fiber assembly and substrate adhesion-dependent cell spreading. Also, it has positive regulation of stem cell proliferation. Tacstd2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Gln25-Gly270\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 28.8 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 38-55 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"50μg","offer_id":43072209715379,"sku":"PKSM041262-50","price":350.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_069b3e84-8f33-442a-9c90-3ee2d64d50af.png?v=1708684075","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-trop2-tacstd2-protein-his-tag-pksm041262","provider":"AFSBio Inc.","version":"1.0","type":"link"}