{"product_id":"recombinant-mouse-vcam1-protein-fc-tag-pksm041260","title":"Recombinant Mouse VCAM1 Protein (Fc Tag) - PKSM041260","description":"\u003cp\u003eRecombinant Mouse VCAM1 Protein (Fc Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSM041260-10, PKSM041260-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: VCAM1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: CD106; Vascular cell adhesion protein 1; Vcam1; L1CAM; VCMA1; Vcam-1\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P29533\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Mouse\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-Fc\u003c\/p\u003e\n\n\u003cp\u003eAccession: P29533\u003c\/p\u003e\n\n\u003cp\u003eBackground: Vascular cell adhesion molecule 1 (VCAM-1) is a cell surface protein belonging to the immunoglobulin superfamily, the protein is expressed by activated endothelial cells and certain leukocytes (such as macrophages). IL-1 beta, IL-4, TNF-alpha and IFN-gamma induced the expression of VCAM-1. The human and mouse VCAM-1 proteins share approximately 76% amino acid similarity. Mouse VCAM-1 is Important in cell-cell recognition. it appears to function in leukocyte-endothelial cell adhesion, and interacts with integrin alpha-4\/beta-1 (ITGA4\/ITGB1) on leukocytes, and mediates both adhesion and signal transduction.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Phe25-Glu698\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 90 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 101.4 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 130 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43072209617075,"sku":"PKSM041260-10","price":155.4,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43072209649843,"sku":"PKSM041260-50","price":415.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_37beb2d4-2b54-4f56-81a3-465039b2363c.png?v=1708684073","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-vcam1-protein-fc-tag-pksm041260","provider":"AFSBio Inc.","version":"1.0","type":"link"}