BmrA transporters are powerful therapeutic targets for multi-drug resistance studies, ideal for therapeutic indications such as bacterial resistance to antibiotics.
CALIXAR’s BmrA transporter (Bacilus subtilis multidrug resistance ABC transporter ATP-binding Protein) is an efflux protein and ABC transporter that acts as a mechanical pump for ATP dependent drug efflux. This unique characteristic makes BmrA transporters a powerful therapeutic target for multi-drug resistance studies.
CALIXAR’s BmrA Transporters aid in the exploration, improvement, validation of novel molecules and therapeutic antibodies. Our BmrA transporters are excellent for therapeutic indications such as bacterial resistance to antibiotics.
Target name: Multidrug resistance ABC transporter ATP-binding/permease protein (BmrA)
Catalogue number: PP3
Class: Multidrug resistance ABC transporter
Sequence: Full-length, wildtype sequence, with a N-terminus 6xHis-tag.
Affinity Tag: His-tag (N-terminal)
Origin: Bacillus subtilis (strain 168)
Theor. MW: 64.5 kDa
Accession #: O06967 (UniProt)
Shipment temperature: Dry Ice
Storage conditions: Store at -80°C
Expression system: Escherichia coli ( BL21C43)
Purification: Immobilized Metal Affinity Chromatography
Activity: Confirmed by ATPase activity assay
Concentration: Up to 5mg/ml
Sample buffer: 50mM Tris-Cl pH 8.0, 100 mM NaCl, 0.01% DDM, 10%glycerol
Available quantity: From 10µg up to mg scale