{"product_id":"recombinant-murine-gro-kc-cxcl1-rmukc-cxcl1-pr2018","title":"Recombinant Murine GRO\/KC\/ CXCL1 (rMuKC\/CXCL1) - PR2018","description":"\u003cp\u003eRecombinant Murine GRO\/KC\/ CXCL1 (rMuKC\/CXCL1)\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PR2018-5, PR2018-20\u003c\/p\u003e\n\n\u003cp\u003eSizes: 5µg, 20µg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: Approximately 7.8kDa, a single non-glycosylated polypeptide chain containing 72 amino acid residues.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt;97% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: Measured by its ability to chemoattract human CXCR2 transfected BaF3 mouse proB cells. \u003cbr\u003e\n The ED50 for this effect is typically 3-15 ng\/mL.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered concentrated solution in PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: APIANELRCQ CLQTMAGIHL KNIQSLKVLP SGPHCTQTEV IATLKNGREA CLDPEAPLVQ KIVQKMLKGV PK\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 1EU\/μg of rMuKC\/CXCL1 as determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\n\u003cp\u003eStorage: This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\n\u003cp\u003eDescription: KC coded by CXCL1 gene at chromosome 5 is approximately 63% identity to that of mouse MIP2. KC is also approximately 60% identical to the human GROs. Mouse KC is a potent neutrophil attractant and activator. The functional receptor for KC has been identified as CXCR2. Based on the pattern of KC expression in a number of inflammatory disease models, KC appears to have an important role in inflammation. KC was found to be involved in monocyte arrest on atherosclerotic endothelium and may also play a pathophysiological role in Alzheimer’s disease.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"5µg","offer_id":42882229600435,"sku":"PR2018-5","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"20µg","offer_id":42882229633203,"sku":"PR2018-20","price":490.83,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_bd4c2797-1f28-492e-b188-882898d73677.jpg?v=1702049695","url":"https:\/\/afsbio.com\/products\/recombinant-murine-gro-kc-cxcl1-rmukc-cxcl1-pr2018","provider":"AFSBio Inc.","version":"1.0","type":"link"}