{"product_id":"recombinant-murine-mcp-2-ccl8-rmumcp-2-ccl8-pr2030","title":"Recombinant Murine MCP-2\/CCL8 (rMuMCP-2\/CCL8) - PR2030","description":"\u003cp\u003eRecombinant Murine MCP-2\/CCL8 (rMuMCP-2\/CCL8)\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PR2030-5, PR2030-20\u003c\/p\u003e\n\n\u003cp\u003eSizes: 5µg, 20µg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 8.5 kDa, a single, non-glycosylated polypeptide chain containing 74 amino acids.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt;97% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: Fully biologically active when compared to standard. Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 10.0-100.0 ng\/ml, corresponding to a Specific Activity of ＞1 x 104 IU\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered concentrated solution in 20mM PB, pH 7.4, 150mM NaCl.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: GPDKAPVTCC FHVLKLKIPL RVLKSYERIN NIQCPMEAVV FQTKQGMSLC\u003cbr\u003e\n VDPTQKWVSE YMEILDQKSQ ILQP\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 1EU\/mg of rMuMCP-2\/CCL8 as determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/ml. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\n\u003cp\u003eStorage: This lyophilized preparation is stable for several weeks at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\n\u003cp\u003eDescription: MCP-2 and MCP-3 are two recently identified monocyte chemotactic proteins produced by human MG-63 osteosarcoma cells. Both MCP-2 and MCP-3 are members of the C-C family of chemokines and share 62% and 71% amino acid sequence identity, respectively, with MCP-1. MCP-3 also shares 58% amino acid identity with MCP-2.\u003cbr\u003e\n Similarly to other C-C chemokines, all three MCP proteins are monocyte chemoattractants. In addition, the three MCPs can chemoattract activated NK cells as well as CD4+ and CD8+ T lymphocytes. All three cytokines have also been shown to attract eosinophils and induce histamine secretion from basophils.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"5µg","offer_id":42882229993651,"sku":"PR2030-5","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"20µg","offer_id":42882230026419,"sku":"PR2030-20","price":490.83,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_3d3fd4ca-502d-4179-a711-88d5ac71e41d.jpg?v=1702049707","url":"https:\/\/afsbio.com\/products\/recombinant-murine-mcp-2-ccl8-rmumcp-2-ccl8-pr2030","provider":"AFSBio Inc.","version":"1.0","type":"link"}