{"product_id":"recombinant-nanog-tat-human-bk0142","title":"Recombinant NANOG-TAT, Human - BK0142","description":"\u003cp\u003eRecombinant NANOG-TAT, Human\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BK0142-20, BK0142-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μg, 100μg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 36.2 kDa, analyzed by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity:\u003c\/p\u003e \n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Sterile Filtered solution contains 10mM PB, 300mM NaCl, pH7.4.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: MSVDPACPQ SLPCFEASDC KESSPMPVIC GPEENYPSLQ MSSAEMPHTE t VSPLPSSMD LLIQDSPDSS TSPKGKQPTS AENSVAKKED KVPVKKQKTR t VFSSTQLCV LNDRFQRQKY LSLQQMQELS NILNLSYKQV KTWFQNQRMK SKRWQKNNWP KNSNGVTQKA SAPTYPSLYS SYHQGCLVNP TGNLPMWSNQ TWNNSTWSNQ TQNIQSWSNH SWNTQTWCTQ SWNNQAWNSP FYNCGEESLQ SCMQFQPNSP ASDLEAALEA AGEGLNVIQQ TTRYFSTPQT MDLFLNYSMN MQPEDVGGYG RKKRRQRRR\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.2 EU\/μg, determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Reconstituted in ddH2O or PBS at 100 μg\/ml.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Recombinant human NANOG-TAT (rhNANOG-TAT) remains stable up to 1-2 weeks at 4°C from date of receipt. For long term storage, aliquot and store at -20°C or -80°C. Avoid repeated freezing and thawing cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.\u003c\/p\u003e\n\n\u003cp\u003eDescription: NANOG is a transcription factor involved with self-renewal of inner cell mass and embryonic stem (ES) cells by functioning in concert with other factors such as POU5F1 (Oct-4) and SOX2. Nanog imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages, and blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes.Recombinant human NANOG-TAT (rhNANOG-TAT) produced in E.coli is a single chain, 318 amino acids non-glycosylated polypeptide. A fully biologically active molecule, rhNANOG-TAT has a molecular mass of 36.2kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"20μg","offer_id":42882245394611,"sku":"BK0142-20","price":375.54,"currency_code":"CAD","in_stock":true},{"title":"100μg","offer_id":42882245427379,"sku":"BK0142-100","price":1152.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_c6b2ab50-ab66-4c88-81b6-8ca3ab7444ee.jpg?v=1702049976","url":"https:\/\/afsbio.com\/products\/recombinant-nanog-tat-human-bk0142","provider":"AFSBio Inc.","version":"1.0","type":"link"}