{"product_id":"recombinant-nedd4-monoclonal-antibody-e-ab-81585","title":"Recombinant NEDD4 Monoclonal Antibody - E-AB-81585","description":"\u003cp\u003eRecombinant NEDD4 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-81585-50, E-AB-81585-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: NEDD4\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: NEDD4; NEDD4-1; RPF1\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Rabbit Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone No.: R06-7C3\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P46934\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 300 μg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human NEDD4\u003c\/p\u003e\n\n\u003cp\u003eBuffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:2000-1:3000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 149kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 115kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"50μL","offer_id":43149044875443,"sku":"E-AB-81585-50","price":224.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":43149044908211,"sku":"E-AB-81585-100","price":364.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_9d68e7ca-8d6f-4b36-b08e-35bcc2e21c30.png?v=1710339156","url":"https:\/\/afsbio.com\/products\/recombinant-nedd4-monoclonal-antibody-e-ab-81585","provider":"AFSBio Inc.","version":"1.0","type":"link"}