{"product_id":"recombinant-osm-mouse-hek293-expre-ssed-bk0326","title":"Recombinant OSM, Mouse (HEK293-expressed) - BK0326","description":"\u003cp\u003eRecombinant OSM, Mouse (HEK293-expre Ssed)\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BK0326-10, BK0326-50\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK 293\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 10-40 kDa, observed by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95% as analyzed by SDS-PAGE and HPLC.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: ED50 \u0026lt; 0.4 ng\/ml, measured in a cell proliferation assay using NIH-3T3 cells.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized after extensive dialysis against PBS.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: ANRGCSNSSSQLLSQLQNQANLTGNTESLLEPYIRLQNLNTPDLRAACTQHSVAFPSEDTLRQLSKPHFLSt VYTTLDRV\u003cbr\u003e\n LYQLDALRQKFLKTPAFPKLDSARHNILGIRNNVFCMARLLNHSLEIPEPTQTDSGASRSTTTPDVFNTKIGSCGFLWGY\u003cbr\u003e\n HRFMGSVGRVFREWDDGSTRSRR\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.2 EU\/μg, determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Reconstituted in ddH2O or PBS at 100 μg\/ml.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Lyophilized recombinant Murine Oncostatin-M remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Murine Oncostatin-M should be stable up to 1 week at 4°C or up to 2 months at -20°C.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Oncostatin-M, also known as OSM, is a growth regulator belonging to the interleukin-6 group of cytokines. It is expressed mainly by monocytes, activated T cells and Kaposi’s sarcoma cells. OSM signals through two types of receptors; one is composed of gp130 and LIFR, and the other is composed of gp130 and OSMR. OSM regulates IL-6, G-CSF and GM-CSF production, and thus is involved in hematopoiesis, neurogenesis and osteogenesis. OSM displays both stimulatory and inhibitory effects, so its categorization as pro-inflammatory or anti-inflammatory cytokine is still controversial.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10μg","offer_id":42882263384243,"sku":"BK0326-10","price":375.54,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":42882263417011,"sku":"BK0326-50","price":1152.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_b94b250e-9cdf-4962-8a36-678c93045542.jpg?v=1702050316","url":"https:\/\/afsbio.com\/products\/recombinant-osm-mouse-hek293-expre-ssed-bk0326","provider":"AFSBio Inc.","version":"1.0","type":"link"}