{"product_id":"recombinant-pdgf-bb-human-p-pastoris-expre-ssed-bk0343","title":"Recombinant PDGF-BB, Human (P. pastoris-expressed) - BK0343","description":"\u003cp\u003eRecombinant PDGF-BB, Human (P.pastoris-expre Ssed)\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BK0343-10, BK0344-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 10μg\u003c\/p\u003e\n\n\u003cp\u003eSource: P. pastoris\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 24.3kDa, observed by non-reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 97% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: ED50 \u0026lt;3 ng\/ml, measured by the dose-dependent stimulation of the proliferation of Balb\/c 3T3 cells, corresponding to a specific activity of \u0026gt;3.3 x 10ˆ5 units\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized after extensive dialysis against 10mM acetic acid.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: SL GSLTIAEPAM IAECKTRTEV FEISRRLIDR TNANFLVWPP CVEVQRCSGC CNNRNVQCRP TQVQLRPVQV RKIEIVRKKP IFKKAt VTLE DHLACKCEt V AAARPVT\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt;1.0 EU\/μg, determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Reconstituted in ddH2O at 100 μg\/ml.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Lyophilized recombinant human Platelet-Derived Growth Factor-BB (rhPDGF-BB) remains stable up to 12 months at -80°C from date of receipt. Upon reconstitution, rhPDGF-BB should be stable up to 4 weeks at 4°C or up to 6 months at -20°C.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Platelet Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle, connective tissue, bone and cartilage cells, and some blood cells. The PDGF is involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. PDGF which is composed of a dimer of two chains termed the A chain and B chain, can be present as AA or BB homodimers or as an AB heterodimer.Recombinant human Platelet-Derived Growth Factor-BB (rhPDGF-BB) produced in Pichia pastoris is a glycosylated polypeptide. rhPDGF-BB is a 24.3 kDa disulfide-linked homodimer of two B chains (218 total amino acids) and is obtained by proprietary chromatographic techniques at GenScript.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10μg","offer_id":42882265252019,"sku":"BK0343-10","price":375.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_53c2154b-c5e6-4d02-a3ae-a7f14f0bfdf8.jpg?v=1702050354","url":"https:\/\/afsbio.com\/products\/recombinant-pdgf-bb-human-p-pastoris-expre-ssed-bk0343","provider":"AFSBio Inc.","version":"1.0","type":"link"}