{"product_id":"recombinant-pdgf-dd-human-bk0281","title":"Recombinant PDGF-DD, Human - BK0281","description":"\u003cp\u003eRecombinant PDGF-DD, Human\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BK0281-10, BK0281-50\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eSource: CHO\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 19-21 kDa, observed by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95% as analyzed by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: ED50 \u0026lt; 5 μg\/ml, measured in a cell proliferation assay using 3T3 cells.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized after extensive dialysis against PBS.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: SYHDRKSKVDLDRLNDDAKRYSCTPRNYSVNIREELKLANVVFFPRCLLVQRCGGNCGCGt VNWRSCTCNSGKt VKKYHE\u003cbr\u003e\n VLQFEPGHIKRRGRAKTMALVDIQLDHHERCDCICSSRPPR\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.2 EU\/μg, determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Reconstituted in ddH2O or PBS at 100 μg\/ml.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Lyophilized recombinant human PDGF-DD remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, human PDGF-DDshould be stable up to 1 week at 4°C or up to 2 months at -20°C.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.\u003c\/p\u003e\n\n\u003cp\u003eDescription: PDGF-DD, also known as platelet-derived growth factor D, IEGF and SCDGFB, is asecreted growth factor belonging to the PDGF\/VEGFfamily. It is highly expressed in the heart, pancreas, adrenal glands and ovary. PDGF-DD forms functional homodimers that bind and induce PDGF Rβ homodimers and PDGF Rα\/β heterodimers that promote intracellular signaling. This plays an important role in the regulation of cell differentiation, migration and survival. It has also been reported that PDGF-DD can induce monocyte and macrophage recruitment, increase interstitial pressure and facilitate wound healing.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10μg","offer_id":42882259615923,"sku":"BK0281-10","price":256.94,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":42882259648691,"sku":"BK0281-50","price":813.32,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_a8204ca9-c1d8-4790-81d7-3fc453bc128c.jpg?v=1702050224","url":"https:\/\/afsbio.com\/products\/recombinant-pdgf-dd-human-bk0281","provider":"AFSBio Inc.","version":"1.0","type":"link"}